PHOSPHOLIPIDS ARE A POTENTIALLY IMPORTANT SOURCE OF TISSUE BIOMARKERS FOR HEPATOCELLULAR CARCINOMA: RESULTS OF A PILOT STUDY INVOLVING TARGETED METABOLOMICS

Phospholipids are A Potentially Important Source of Tissue Biomarkers for Hepatocellular Carcinoma: Results of a Pilot Study Involving Targeted Metabolomics

Background: Hepatocellular carcinoma (HCC) pathogenesis involves the alteration of multiple liver-specific metabolic pathways.We systematically profiled cancer- and liver-related classes of metabolites in HCC and adjacent liver tissues and applied supervised machine learning to compare their potential yield for HCC biomarkers.Methods: Tumor and cor

read more



Quantifying the fragility of coral reefs to hurricane impacts: a case study of the Florida Keys and Puerto Rico

Ecosystems like coral reefs mitigate rising coastal flood risks, but investments into their conservation remain low relative to the investments into engineered risk-mitigation structures.One reason is that quantifying the risk-reduction benefits of coral reefs requires an estimate of their fragility to severe stresses.Engineered structures typicall

read more